Achtergronden

The pros and cons of phytoestrogens
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074428/

Onderzoek naar voorkeuren
http://www.jphysiolanthropol.com/content/pdf/1880-6805-31-13.pdf

Vernieuwde inzichten over vitamine K2 (menquinone-7
http://www.orthokennis.nl/ResearchItem.asp?IDResearch=74

Over vitamine k1 en k2
http://naturafoundation.nl/?objectID=45&action=pdf&id=41519

Vitamine K2 bij botontkalking en aderverkalking
http://www.tigweb.nl/TIG23_19_de_Munck-Khoe_-_Vitamine_K2.pdf

The vitamin K
http://menaq7.com/k-vitamins-overview/what-are-k-vitamins/

Referenties (voor wie de onderzoeken wil

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  2. Vermeer C, Shearer MJ, Zittermann A et al. Beyond deficiency: potential benefits of increased intakes of vitamin K for bone and vascular health. Eur J Nutr. 2004;43(6):325-35.
  3. Cranenburg EC, Schurgers LJ, Vermeer C. Vitamin K: the coagulation vitamin that became omnipotent. Thromb Haemost. 2007;98(1):120-5.
  4. Hasanbasic I, Rajotte I, Blostein M. The role of gamma-carboxylation in the anti-apoptotic function of gas6. J Thromb Haemost. 2005;3(12):2790-7.
  5. Otsuka M, Kato N, Ichimura T et al. Vitamin K2 binds 17beta-hydroxysteroid dehydrogenase 4 and modulates estrogen metabolism. Life Sci 2005;76:2473-82.
  6. Nagasawa Y, Fujii M, Kajimoto Y et al. Vitamin K2 and serum cholesterol in patients on continuous ambulatory peritoneal dialysis. Lancet 1998;351:724.
  7. Schurgers LJ, Vermeer C. Determination of phylloquinone and menaquinones in food: effect of food matrix on circulating vitamin K concentrations. Haemostasis 2000;30:298-307.
  8. van Summeren M, Braam L, Noirt F et al. Pronounced elevation of undercarboxylated osteocalcin in healthy children. Pediatr Res. 2007;61(3):366-70.
  9. Booth SL, Broe KE, McLean RR et al. Low vitamin K status is associated with low bone mineral density and quantitative ultrasound in men. J Bone Miner Res 2002;17(Suppl 1):S200.
  10. Booth SL, Tucker KL, Chen H et al. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr 2000;71:1201-1208.
  11. Booth SL, Broe KE, Gagnon DR et al. Vitamin K intakes and bone mineral density in women and men. Am J Clin Nutr 2003;77:512-516.
  12. Feskanich D,Weber P,Willett WC et al. Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr 1999;69:74-79.
  13. Vergnaud P, Garnero P, Meunier PJ et al. Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study. J Clin Endocrinol Metab 1997;82:719 –24.
  14. Shea MK, Booth SL. Role of vitamin K in the regulation of calcification. International Congress Series 2007;1297:165–178.
  15. Katsuyama H, Ideguchi S, Fukunaga M et al. Promotion of bone formation by fermented soybean (Natto) intake in premenopausal women. J Nutr Sci Vitaminol (Tokyo). 2004;50(2):114-20.
  16. Kaneki M, Hodges SJ, Hosoi T et al. Japanese fermented soybean food as the major determinant of the large geographic difference in circulating levels of vitamin K2: possible implications for hip-fracture risk. Nutrition. 2001;17(4):315-21.
  17. Braam LA, Knapen MH, Geusens P et al. Vitamin K1 supplementation retards bone loss in postmenopausal women between 50 and 60 years of age. Calcif Tissue Int. 2003;73:21-26.
  18. Knapen MH, Schurgers LJ, Vermeer C. Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007;18(7):963-72.
  19. Shiraki M, Shiraki Y, Aoki C et al. Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res 2000;15:515-21.
  20. Schurgers LJ, Teunissen KJ, Hamulyak K et al. Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone- 7. Blood. 2007;109(8):3279-83.
  21. T. Neogi, et al., Low vitamin K status is associated with osteoarthritis in the hand and knee. Arthritis Rheum. 2006;54:1255-1261.
  22. Schurgers LJ, Spronk HM, Soute BA et al. Regression of warfarin-induced medial elastocalcinosis by high intake of vitamin K in rats. Blood. 2007;109(7):2823- 31.
  23. Braam LA, Hoeks AP, Brouns F et al. Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: a follow-up study. Thromb Haemost. 2004;91(2):373-80.
  24. Schurgers LJ, Teunissen KJ, Knapen MH et al. Novel conformation-specific antibodies against matrix gamma}-carboxyglutamic acid (Gla) protein. Undercarboxylated matrix gla protein as marker for vascular calcification. Arterioscler Thromb Vasc Biol 2005;25:1629-33.
  25. Geleijnse JM, Vermeer C, Grobbee DE et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr. 2004;134(11):3100-5.
  26. Tsugawa N, Shiraki M, Suhara Y et al. Vitamin K status of healthy Japanese women: age-related vitamin K requirement for gamma-carboxylation of osteocalcin. Am J Clin Nutr. 2006;83(2):380-6.
  27. Braam LA, Knapen MH, Geusens P et al. Factors affecting bone loss in female endurance athletes: a twoyear follow-up study. Am J Sports Med. 2003;31:889- 895.
  28. Iketani T, Kiriike N, Murray et al. Effect of menatetrenone (vitamin K2) treatment on bone loss in patients with anorexia nervosa. Psychiatry Res. 2003;117(3):259-69.
  29. Horiuchi T, Kazama H, Araki A et al. Impaired gamma carboxylation of osteocalcin in elderly women with type II diabetes mellitus: relationship between increase in undercarboxylated osteocalcin levels and low bone mineral density. J Bone Miner Metab. 2004;22(3):236- 40.
  30. Jie K-SG,Bots ML, Vermeer C et al. Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: a population-based study. Atherosclerosis 1995;116:117-123.